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Chemokines and Alzheimer's disease

W J Streit1, J R Conde, J K Harrison

  • 1Department of Neuroscience, University of Florida College of Medicine and McKnight Brain Institute, Gainesville, FL 32611, USA. streit@ufbi.ufl.edu

Neurobiology of Aging
|January 5, 2002
PubMed
Summary

Chemokines are inflammatory mediators in the central nervous system (CNS). This review highlights their role in Alzheimer's disease (AD) pathogenesis and neuron-microglia communication, suggesting impaired communication may affect microglial function.

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