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Morphological analysis of developmental changes in pontine noradrenergic neuronal groups in the neonatal rat
Yoko Ito1, Yoshitaka Oyamada, Haruhiko Hakuno
1Department of Medicine, School of Medicine, Keio University, 35 Shinano-machi, Shinjuku-ku, Tokyo 160-8582, Japan.
Brain Research
|January 5, 2002
Abstract:
We examined the morphological changes in two pontine noradrenergic neuronal groups, area A5 and the locus coeruleus (LC), in neonatal Sprague-Dawley rats between postnatal day 1 and day 10. The volume of the unilateral LC exhibited no significant developmental change. Meanwhile, the number of A5 neurones counted unilaterally was significantly larger on days 1-2 than on days 3-4 or day 10.