Related Experiment Videos
Prophylactic antipyretic treatment with acetaminophen in acute ischemic stroke: a pilot study
1Neurologische Abteilung, Stroke Unit, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Germany. h.koennecke@keh-berlin.de
Neurology
|January 5, 2002
Abstract:
Fever is associated with poor outcome in acute stroke. Forty-two consecutive, normothermic patients with acute ischemic stroke were, within 24 hours from symptom onset, randomized to either receive 4 g acetaminophen daily (n = 20) or matched placebo (n = 22). Fever of greater than 37.5 degrees C occurred in 36.4% of patients in the placebo group, compared with 5.0% in the acetaminophen group (Fisher's exact test, p = 0.014). Prophylactic antipyretic treatment with acetaminophen may be effective in the prevention of fever after acute ischemic stroke.