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Related Experiment Videos

Interrelationships of selenium with other trace elements.

C H Hill

    Federation Proceedings
    |October 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Selenium

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    Area of Science:

    • Environmental Toxicology
    • Nutritional Biochemistry
    • Trace Element Research

    Background:

    • Selenium's toxicity is influenced by interactions with other elements.
    • Arsenic, mercury, cadmium, and copper are known to interact with selenium.
    • Selenium can also mitigate the toxicity of mercury and cadmium.

    Purpose of the Study:

    • To investigate biological interactions between selenium and other trace elements.
    • To understand how these interactions affect selenium's toxicity.
    • To explore the impact of selenium on the toxicity of other elements.

    Main Methods:

    • Studies involving various animal species under diverse conditions.
    • Analysis of reaction products of selenium with mercury and cadmium.

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  • Observation of selenium excretion patterns with arsenic exposure.

    • Main Results:

    • Biological interactions significantly reduce selenium's toxicity.
    • Reaction products of selenium with mercury and cadmium show lower toxicity.
    • Arsenic exposure alters selenium excretion pathways, directing it to bile.
    • No definitive evidence suggests reduced selenium absorption or retention due to other elements.

    Conclusions:

    • Interactions with elements like arsenic, mercury, cadmium, and copper decrease selenium toxicity.
    • Selenium can reduce the toxicity of mercury and cadmium.
    • Formation of less reactive compounds may explain these observed interactions.