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Reference values for the five electrophoretic serum protein fractions in Caucasian children by capillary zone

X Bossuyt1, R Claeys, G Bogaert

  • 1Laboratory Medicine, Immunology, University Hospital, KU Leuven, Belgium. Xavier.Bossuyt@uz.kuleuven.ac.be

Clinical Chemistry and Laboratory Medicine
|January 5, 2002
PubMed

Insights

This study establishes age-specific reference intervals for capillary zone electrophoresis in children aged 1 to 14 years. These findings provide crucial benchmarks for pediatric clinical diagnostics.

Area of Science:

  • Clinical Chemistry
  • Pediatric Laboratory Medicine
  • Analytical Biochemistry

Background:

  • Capillary zone electrophoresis (CZE) is a valuable analytical technique.
  • Establishing age-specific reference intervals is essential for accurate interpretation of CZE results in pediatric populations.

Purpose of the Study:

  • To determine age-related reference intervals for capillary zone electrophoresis parameters in healthy children.
  • To provide normative data for the pediatric age group (1-14 years).

Main Methods:

  • Capillary zone electrophoresis was performed on capillary blood samples.
  • Analysis included key electrophoretic parameters.
  • Data were analyzed to establish age-stratified reference intervals.

Main Results:

  • Age-related reference intervals for capillary zone electrophoresis were successfully established for children aged 1 to 14 years.
  • Significant age-dependent variations were observed for several parameters.

Conclusions:

  • The established reference intervals provide essential benchmarks for interpreting CZE results in pediatric patients.
  • These data support the accurate clinical assessment and diagnosis in children.

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