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Updated: Aug 11, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
Abstract:
Numerous epidemiological studies have disclosed documented evidence that light to moderate consumption of any alcoholic beverage is associated with approximately 20% reduction in cardiovascular disease risk. This finding applies to both men and women and to healthy individuals as well as those with coronary heart disease, diabetes, hypertension, or heart failure. Nevertheless, the issue of including a recommendation for mild to moderate alcohol consumption within the routine recommendations for primary and secondary prevention of coronary heart disease is still controversial. The controversy is derived partly from methodological issues and partly from documented adverse health effects of excessive alcohol drinking. The key issue is the definition of the optimal dose of alcohol which guarantees a positive benefit-risk ratio, i.e. enjoying the benefits of alcohol without substantial risk. The accumulating scientific evidence shows that a daily consumption of less than 30 grams of alcohol for men and less than 15 grams for women is compatible with the above goal and is not associated with health risks. Therefore, for most individuals it is appropriate to recommend mild to moderate alcohol consumption as part of a healthy life style for the prevention of cardiovascular disease. Recommendations should be given on an individual basis, taking into account the patient's age, gender, physical and mental health status, personality and past drinking habits. The desirable quantity and its upper limit as well as drinking patterns should be clearly defined. All persons should be warned to avoid heavy drinking. Awareness of indications for abstinence from alcohol such as pregnancy, sport activity and the use of certain medications is highly important.
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