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Mineralized corneal sequestrum in a cat.

A J Gemensky1, D A Wilkie

  • 1Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University Columbus 43210, USA.

Journal of the American Veterinary Medical Association
|January 5, 2002
PubMed
Summary

Mineralized corneal sequestrum, a rare feline eye condition, occurred in a cat after corticosteroid treatment. This condition, potentially linked to feline herpesvirus-1, involves corneal necrosis and mineralization.

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Area of Science:

  • Veterinary Ophthalmology
  • Ophthalmology
  • Feline Medicine

Background:

  • Corneal sequestrum is a common condition in cats, often associated with feline herpesvirus-1 (FHV-1).
  • Corticosteroids are frequently used to manage ocular inflammation but can have side effects.

Observation:

  • A case of chronic refractory keratitis with a mineralized corneal plaque in an 8-month-old cat.
  • Clinical signs included blepharospasm, conjunctivitis, corneal vascularization, and a dense, gritty corneal plaque.

Findings:

  • Histopathology revealed coagulation necrosis, mineralization of the corneal stroma, inflammation, vascularization, and fibrosis.
  • The condition was diagnosed as a mineralized corneal sequestrum, potentially exacerbated by topical corticosteroid use.

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Implications:

  • This is the first reported clinical case of a mineralized corneal sequestrum in a cat.
  • The findings suggest that corticosteroid use may potentiate corneal necrosis and mineralization in cats with underlying FHV-1 infections.