[Myocarditis simulating myocardial infarction]
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Updated: Sep 25, 2026

Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
Abstract:
Acute myocarditis caused by infectious mononucleosis simulated myocardial infarction, initially the quantitative and qualitative blood picture was normal. Repeated blood and serological studies confirmed the diagnosis, which was altered by acute porphyria caused by infection. In each case of young patients with myocardial infarction and in older patient with coexisting infectious symptoms, myocarditis must be considered. Since the cardiac manifestation may precede the infectious disease symptoms, repeating the necessary examinations may be mandatory.
Insights
Infectious mononucleosis can mimic heart attack symptoms. Myocarditis, an inflammation of the heart muscle, should be considered in young patients with heart attack symptoms, especially if infection is present.
Area of Science:
- Cardiology
- Infectious Diseases
- Hematology
Background:
- Myocarditis, inflammation of the heart muscle, can present with symptoms mimicking myocardial infarction.
- Infectious mononucleosis is a common viral illness that can have varied clinical presentations.
Observation:
- A case where acute myocarditis, secondary to infectious mononucleosis, initially presented as myocardial infarction.
- Initial blood work was unremarkable, delaying the correct diagnosis.
- Subsequent blood and serological tests were crucial for diagnosis.
Findings:
- The diagnosis was revised to include acute porphyria, also triggered by infection.
- Cardiac manifestations of infection can precede overt signs of the infectious disease.
Implications:
- Myocarditis should be a differential diagnosis in young patients presenting with myocardial infarction.
- Consider myocarditis in older patients with myocardial infarction and concurrent infectious symptoms.
- Repeated diagnostic evaluations may be necessary when cardiac symptoms appear before infectious disease symptoms are evident.
Related Concept Videos
Myocarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis III: Medical Management
Myocarditis IV: Nursing Management
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

