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The human leukocyte test system. VI. The use of sister chromatid exchanges as possible indicators for mutagenic
Humangenetik
|September 10, 1975
Abstract:
The trifunctional alkylating chemical mutagen trenimon increases the frequency of sister chromatid exchanges in human leukocyte chromosomes in vitro, as revealed by a BUdR-Giemsa method. Treatment with lead acetate exhibited negative results in this respect. The use of sister chromatid exchanges as possible indicators for mutagenic activities is discussed.