Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Pathogenesis of exercise induced asthma].

W Medrala, A Wolańczyk-Medrala, T Tomkowicz

    Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
    |January 5, 2002
    PubMed
    Summary

    Exercise-induced asthma involves exaggerated airway responses to dehydration, leading to airway narrowing primarily from smooth muscle contraction. This study explores proposed hypotheses explaining the pathomechanism of this bronchial hyperreactivity.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The -2549 -2567 del18 Polymorphism in VEGF and Irreversible Bronchoconstriction in Asthmatics.

    Journal of investigational allergology & clinical immunology·2018
    Same author

    Can obstructive intralymphatic granulomas be the cause of cheilitis granulomatosa?

    Lymphology·2018
    Same author

    Immunosuppressive Treatment and Its Effect on the Occurrence of Pneumocystis jiroveci, Mycoplasma pneumoniae, Chlamydophila pnemoniae, and Legionella pneumophila Infections/Colonizations Among Lung Transplant Recipients.

    Transplantation proceedings·2018
    Same author

    Bacterial Infections During Hospital Stay and Their Impact on Mortality After Lung Transplantation: A Single-Center Study.

    Transplantation proceedings·2018
    Same author

    Aspirin does not preferentially potentiate IgE-dependent basophil CD63 upregulation in patients with food-dependent exercise-induced anaphylaxis.

    Journal of investigational allergology & clinical immunology·2015
    Same author

    Naproxen increases the severity of food-dependent exercise-induced anaphylaxis: a case report.

    Journal of investigational allergology & clinical immunology·2015

    Area of Science:

    • Respiratory Medicine
    • Pulmonology
    • Exercise Physiology

    Background:

    • Exercise-induced asthma (EIA) is characterized by exaggerated airway narrowing following physical exertion.
    • Key triggers include airway dehydration and the subsequent release of inflammatory mediators.
    • Pathological mechanisms involve bronchial smooth muscle contraction, mucus production, edema, and cough.

    Discussion:

    • This review synthesizes current and historical hypotheses on EIA's pathomechanism.
    • Focuses on the interplay between airway dehydration and inflammatory responses.
    • Highlights bronchial smooth muscle hyperreactivity as a central feature.

    Key Insights:

    • Airway dehydration is a critical initial event in EIA.
    • Inflammatory mediators play a significant role in airway narrowing.

    Related Experiment Videos

  • Bronchial smooth muscle contraction is the primary cause of airway narrowing in EIA.

    • Outlook:

    • Further research is needed to fully elucidate the complex pathomechanism of EIA.
    • Investigating novel therapeutic targets for managing exercise-induced asthma.
    • Understanding EIA's pathomechanism can improve patient management and quality of life.