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Updated: Jul 30, 2026
11:10
Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
Published on: November 16, 2011
Information technology and home glucose clamping.
A M Albisser1, S C En Chao, I D Parson
1Disease Management Division, Better Control Medical Computers, Inc., Miami Beach, Florida 33139, USA. Albisser@nidm.org
Diabetes Technology & Therapeutics
|January 5, 2002
Summary
A new information technology system helped people with diabetes manage blood glucose at home. This system reduced diabetes-related crises by half and lowered A1C levels, empowering patients in their self-care.
Area of Science:
- Biomedical Engineering
- Health Informatics
- Endocrinology
Background:
- Diabetes self-management is crucial for glycemic control.
- Existing methods for glucose control can be challenging for patients.
- Home-based decision support systems are needed to improve diabetes care.
Purpose of the Study:
- To develop and evaluate an information technology system for home glucose clamping.
- To empower patients with diabetes in their daily self-management.
- To improve clinical outcomes through enhanced self-blood glucose control.
Main Methods:
- Adapted laboratory glucose clamping algorithms for home use via telephone.
- Implemented a central computer system with voice response hardware.
- Patients reported glucose levels and lifestyle events; received automated instructions and dosing support.
Main Results:
- A twofold reduction in diabetes-related crises (hyperglycemia/hypoglycemia).
- A 1.3% decrease in glycated hemoglobin (HbA1c) levels.
- Stable body weight and provider benefits from standardized patient reports.
Conclusions:
- Information technology effectively facilitates home glucose clamping for diabetes self-management.
- The system empowers patients with diabetes, leading to improved glycemic control and reduced crises.
- This approach enhances patient independence and supports timely clinical intervention.
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