Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bioartificial pancreas: materials, devices, function, and limitations.

A Prokop1

  • 1Chemical Engineering Department, Vanderbilt University, Nashville, TN 37235, USA. ales.prokop@mcmail.vanderbilt.edu

Diabetes Technology & Therapeutics
|January 5, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Internal Otic Region of Oromerycids (Artiodactyla, Oromerycidae), Early Camelids (Artiodactyla, Camelidae), and the Vicuña (Artiodactyla, Camelidae), Including Notes on Intraspecific and Subadult Ontogenetic Variation.

Integrative organismal biology (Oxford, England)·2025
Same author

Zeitschrift fur Orthopadie und Unfallchirurgie·2018
Same author

Zentralblatt fur Chirurgie·2017
Same author

Zeitschrift fur Orthopadie und Unfallchirurgie·2017
Same author

Zeitschrift fur Orthopadie und Unfallchirurgie·2017
Same author

Biosystem models, generated from a complex rule/reaction/influence network and from two functionality prototypes.

Bio Systems·2017
Same journal

<i>Letter:</i> "Nocturnal Hypoglycemia: Characterization with Continuous Glucose Monitoring in a Real-World Setting".

Diabetes technology & therapeutics·2026
Same journal

Transient Benign Ketosis Is Common in Type 1 Diabetes During Very-Low Carbohydrate States: Novel Data from Continuous Ketone Sensor.

Diabetes technology & therapeutics·2026
Same journal

Budget Impact of Advanced Insulin Delivery Systems for the Management of Type 1 Diabetes.

Diabetes technology & therapeutics·2026
Same journal

Continuous Glucose Monitoring and Hypoglycemia Detection while Driving: Results from a Cross-Sectional Survey.

Diabetes technology & therapeutics·2026
Same journal

<i>Erratum to:</i> "HbA1c and Glucose Management Indicator Discordance: A Real-World Analysis".

Diabetes technology & therapeutics·2026
Same journal

<i>Letter:</i> Comments on: Real-World Total Daily Insulin Dose in over 14,000 Young Individuals with Type 1 Diabetes in the United States.

Diabetes technology & therapeutics·2026
See all related articles

The bioartificial pancreas (BAP) concept, evolving from bioartificial endocrine pancreas (BEP), utilizes microencapsulated islets for artificial beta-cells. This technology aims to protect transplanted cells from immune rejection, offering a potential diabetes treatment.

Area of Science:

  • Biomedical Engineering
  • Endocrinology
  • Immunology

Background:

  • The concept of a bioartificial endocrine pancreas (BEP) was introduced in 1980.
  • Microencapsulated islets as artificial beta-cells were proposed in 1968.
  • Semipermeable membranes protect transplanted islets from immune rejection.

Purpose of the Study:

  • To trace the evolution of terminology in the field of artificial pancreas research.
  • To differentiate between bioartificial endocrine pancreas (BEP) and bioartificial pancreas (BAP).
  • To define the scope and components of a bioartificial pancreas (BAP).

Main Methods:

  • Historical review of scientific literature and terminology.
  • Analysis of the defining characteristics of BEP and BAP.

Related Experiment Videos

  • Comparison of encapsulation techniques and protective vehicles.

    • Main Results:

    • The term BEP is less common; BAP is now widely used.
    • BAP encompasses a broader range of applications beyond filtration-barrier systems.
    • BAP includes endocrine cells and protective vehicles, not necessarily requiring precise filtration.

    Conclusions:

    • BAP represents an evolution and broadening of the original BEP concept.
    • The terminology shift reflects advancements and diverse approaches in artificial pancreas development.
    • Understanding the distinction is crucial for research and therapeutic applications.