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[Zinc therapy in acrodermatitis enteropathica].

N Thyresson

    Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
    |August 1, 1975
    PubMed
    Summary

    Severe acrodermatitis enteropathica (AE) in two patients, including a 20-year-old, was completely resolved with oral zinc therapy. This highlights zinc

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    Area of Science:

    • Dermatology
    • Human Physiology
    • Nutritional Science

    Context:

    • Acrodermatitis enteropathica (AE) is a rare genetic disorder of zinc absorption.
    • Severe AE symptoms can significantly impact patient quality of life.
    • Previous treatments have varied in efficacy.

    Purpose:

    • To report successful treatment of severe acrodermatitis enteropathica with oral zinc.
    • To discuss the potential mechanism of zinc deficiency in AE.

    Summary:

    • Two patients with acrodermatitis enteropathica (AE), one presenting with severe symptoms at age 20, were treated with oral zinc.
    • Complete clinical resolution of AE symptoms was achieved within two months of oral zinc supplementation.
    • The findings support the role of zinc in managing AE.

    Impact:

    • Oral zinc therapy offers a highly effective treatment for acrodermatitis enteropathica.
    • This case study reinforces the importance of addressing zinc deficiency in dermatological conditions.
    • Further research into zinc metabolism in AE is warranted.

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