Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Lichen planus pigmentosus-inversus.

L Pock¹, L Jelínková, L Drlík

¹Department of Dermatology and Venerology, Charles University 2nd Medical School, Motol University Hospital, Prague, Czech Republic. lumir.pock@atlas.cz

Journal of the European Academy of Dermatology and Venereology : JEADV

|January 5, 2002

Summary

This study identifies a variant of lichen planus pigmentosus (LPP) predominantly affecting intertriginous areas, termed LPP-inversus. Microscopic findings reveal unique inflammatory and degenerative processes contributing to its presentation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

World vitiligo day: a model for grassroots medical activism and pharmaceutical innovation.

Frontiers in medicine·2025

Same author

Compliance, safety concerns and anxiety in patients treated with biologics for psoriasis during the COVID-19 pandemic national lockdown: a multicenter study in the Czech Republic.

Journal of the European Academy of Dermatology and Venereology : JEADV·2020

Same author

Gentamicin 240 mg plus azithromycin 2 g vs. ceftriaxone 500 mg plus azithromycin 2 g for treatment of rectal and pharyngeal gonorrhoea: a randomized controlled trial.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2019

Same author

AURIEL-PsO: a randomized, double-blind phase III equivalence trial to demonstrate the clinical similarity of the proposed biosimilar MSB11022 to reference adalimumab in patients with moderate-to-severe chronic plaque-type psoriasis.

The British journal of dermatology·2019

Same author

[Corifollitropin alfa in women stimulated for the first time in in vitro fertilization programme].

Ceska gynekologie·2017

Same author

[Successful ovarian tissue transplantation in woman with premature ovarian failure after gonadotoxic treatment].

Ceska gynekologie·2017

Area of Science:

Dermatology
Pathology

Background:

Lichen planus pigmentosus (LPP) is a skin condition characterized by hyperpigmentation.
Typical LPP lesions can present in various forms and locations.

Purpose of the Study:

To investigate the clinical and microscopic features of LPP in seven patients.
To propose a new designation for a variant of LPP with distinct characteristics.

Main Methods:

Clinical examination of seven patients with LPP.
Microscopic examination of skin biopsies from affected individuals.

Main Results:

All patients exhibited a predominance of LPP lesions in intertriginous areas, particularly the axillae.
Microscopic analysis revealed active inflammation with intense hydropic degeneration of basal keratinocytes and absence of acanthosis.

Related Experiment Videos

These findings suggest a rapid transition to a regressive phase with pigment incontinence.

Conclusions:

The unique morphogenetic dynamics and inverse location support the designation of LPP-inversus for this variant.
LPP-inversus presents as brown, non-pruritic, small inflammatory macules due to specific pathological processes.