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Neisseria meningitidis native valve endocarditis. A case report.
1Department of Medicine and Cardiology, Garcia de Orta Hospital, Almada. fg.ijg@mail.telepac.pt
Summary
Neisseria meningitidis, a bacterium not typically causing heart infections, was found to cause endocarditis in a diabetic patient. Prompt penicillin treatment led to recovery, resolving fever, neurological symptoms, and valve vegetation.
Area of Science:
- Infectious Diseases
- Cardiology
- Neurology
Background:
- Nonpathogenic Neisseria species are common upper respiratory tract commensals.
- Neisseria meningitidis is primarily known for causing meningitis and sepsis.
- Infective endocarditis is an uncommon manifestation of Neisseria meningitidis infection.
Observation:
- A 64-year-old male with type II diabetes presented with fever, aphasia, and right hemiparesis.
- Cardiac examination revealed a systolic murmur, and blood cultures were positive for Neisseria meningitidis.
- Echocardiography identified a vegetation on the mitral valve posterior leaflet.
Findings:
- The patient was diagnosed with meningococcal endocarditis.
- Intravenous penicillin therapy resulted in clinical improvement.
- Resolution of fever, neurological deficits, and mitral valve vegetation was observed.
Implications:
- This case highlights Neisseria meningitidis as a potential cause of infective endocarditis, even in immunocompetent individuals.
- Early diagnosis and appropriate antibiotic treatment are crucial for favorable outcomes.
- Further research may elucidate the specific mechanisms and risk factors for meningococcal endocarditis.