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Serum soluble interleukin 2 receptor levels and radiological progression in early rheumatoid arthritis
J P Camilleri1, N Amos, B D Williams
1Rheumatology Department, University Hospital of Wales and School of Medicine, Cardiff, UK. jeremy.camilleri@uhw-tr.wales.nhs.uk
Objective:
To investigate the association between serum soluble interleukin 2 receptor (sIL-2R) levels and radiological changes in patients with early rheumatoid arthritis (RA).
Methods:
sIL-2R levels from 155 patients with active RA were measured by immunoassay over a 2 year period and the associations with radiological change and other measures of disease activity were analyzed.
Results:
The area under the curve for sIL-2R is weakly associated with the change in the modified Larsen score over a 2 year period; this is weaker than the association of radiological change with serum C-reactive protein.
Conclusion:
We found no significant association of sIL-2R levels with erosive change in early RA.