Synthesis and antiviral assays of some benzimidazole nucleosides and acyclonucleosides
L Garuti1, M Roberti, G Gentilomi
1Department of Pharmaceutical Science, University of Bologna, Italy. lauga@alma.unibo.it
Farmaco (Societa Chimica Italiana : 1989)
|January 5, 2002
Abstract:
Some benzimidazole nucleosides and acyclonucleosides were synthesized and tested in vitro as antiviral agents. None of them showed significant activity. Replacement of the benzenesulphonyl group at N-1 with the ribofuranosyl moiety or with the acyclovir side-chain was deleterious.
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