Effects of repeated administrations of a comprehensive neuropsychological battery among chronic epileptics

Effects of repeated administrations of the neuropsychological battery originated by Halstead and developed by Reitan were assessed by administration of the battery on four occasions at 6- to 12-month intervals to 17 epileptics with stable neurological dysfunction. Changes in drug regimen complicated interpretation to some degree, but it appeared that: a) the majority of the neuropsychological measures did not demonstrate significant practice effects; and b) there were statistically and clinically significant practice effects on some of Halstead's most sensitive measures (Category Test, Tactual Performance Test--Localization, Impairment Index). In addition, the question was raised as to whether or not the Wechsler Adult Intelligence Scale may be more effected by the administration of anticonvulsants than are many of the other neuropsychological procedures. Caution was urged in interpretation when the battery is used on a repeated basis.