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Rabies exposures in thai children.

C Pancharoen1, U Thisyakorn, W Lawtongkum

  • 1Department of Pediatrics, Chulalongkorn University Hospital, and Queen Saovabha Memorial Institute, Thai Red Cross Society, Bangkok. chadapanch@usa.net

Wilderness & Environmental Medicine
|January 5, 2002
PubMed
Summary

Rabies exposures in Thai children, primarily from dog bites, are a significant public health issue. Cost-effective treatments like reduced-dose intradermal vaccines and equine rabies immunoglobulin are recommended.

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Area of Science:

  • Epidemiology
  • Public Health
  • Infectious Disease Prevention

Background:

  • Rabies remains a critical concern, particularly for pediatric populations in endemic regions.
  • Understanding the patterns of potential rabies exposure is vital for effective public health interventions.

Purpose of the Study:

  • To investigate the epidemiology of potential rabies exposures among children in Thailand.
  • To identify risk factors and common scenarios associated with rabies exposure in pediatric cases.

Main Methods:

  • Retrospective review of medical records for children (0-14 years) with potential rabies exposures.
  • Data collection included demographics, exposure source, location, and treatment administered.

Main Results:

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  • 2622 children studied; 86.3% of exposures were dog-related, often unprovoked attacks near homes.
  • Lower extremities were the most common site of exposure.
  • All received rabies vaccine; 57.5% received rabies immunoglobulin (RIG), including human (HRIG) and equine (ERIG) forms.

Conclusions:

  • Pediatric rabies exposures represent a substantial public health challenge in Thailand.
  • Reduced-dose, intradermal vaccination and the use of equine rabies immunoglobulin (ERIG) offer cost-effective treatment strategies.