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Pancreatoblastoma.

V Kaushal1, A Goel, K N Rattan

  • 1Department of Radiotherapy, 35/9J, Medical Enclave Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak. vkaushal@vsnl.com

Indian Journal of Pediatrics
|January 5, 2002
PubMed
Summary
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This case study highlights a rare pediatric pancreatoblastoma, a childhood pancreatic tumor. Complete surgical excision of this large, localized tumor resulted in a positive outcome for the patient.

Area of Science:

  • Pediatric Oncology
  • Surgical Oncology
  • Gastrointestinal Pathology

Background:

  • Pancreatoblastoma is an exceedingly rare pancreatic neoplasm in pediatric patients, accounting for only 0.5% of non-endocrine pancreatic tumors.
  • Fewer than 50 cases were documented in medical literature prior to 1997, underscoring its rarity.

Observation:

  • A 10-year-old male presented with a large abdominal mass of 9 months' duration.
  • Imaging revealed a significant lobulated mass anterior to the portal and splenic veins.
  • Surgical exploration identified a large, localized pancreatic mass in the body and tail, amenable to complete resection.

Findings:

  • Histopathological examination confirmed the diagnosis of pancreatoblastoma.
  • The resected tumor measured 25 x 20 x 15 cm and weighed 2.5 kg, representing the largest reported case.

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  • The patient remained disease-free 6 months post-operatively following complete tumor excision.

    • Implications:

    • Aggressive surgical management of resectable pancreatoblastoma can lead to curative outcomes.
    • The optimal role for adjuvant chemotherapy or radiotherapy remains under investigation due to limited patient data.
    • This case expands the understanding of large, localized pancreatoblastoma and successful surgical management in children.