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[An investigation on morphology of experimental corneal neovascularization]
Objective:
To observe the morphologic character of the corneal neovascularization in experimental rabbits and also compare it with the morphology of that after irradiation with beta-rays.
Methods:
A model of new blood vessels on the corneas of New Zealand rabbits was established with silver nitrate burning. The growth character of the neovascularization was compared between the irradiated and non-irradiated groups. The casting of the new blood vessels in different periods was made and the morphologic differences between the two groups were compared under a scanning electron microscope.
Results:
The corneal new blood vessels occurred and continuously proliferated with the typical method of budding. The formation of buds was obviously inhibited and damaged after irradiation with or beta-rays, and the irradiated new branches were also atrophic and necrotic.
Conclusions:
Stopping the budding procedure of the corneal neovascularization may inhibit the formation and development of the corneal new blood vessels.