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[Changes of pulmonary function and partial oxygen pressure before and after bronchoalveolar lavage in patients with
1Institute of Respiratory Disease, First Clinical College, China Medical University, Shenyang 110001, China.
Objective:
To study the influence of bronchoalveolar lavage(BAL) on pulmonary physiological function and partial oxygen pressure(PaO2).
Methods:
Pulmonary function and partial oxygen pressure were measured in 42 patients with interstitial lung disease (ILD) before and after BAL, 7 non-smoker volunteers as control group.
Results:
VC% and FEV1% decreased significantly from (74 +/- 17)% to (64 +/- 19)% and from (72 +/- 9)% to (65 +/- 12)%, respectively. PaO2 decreased from(77 +/- 11) mm Hg to (63 +/- 11) mm Hg. The above parameters were also decreased in control group, but had no statistical significance.
Conclusion:
Pulmonary physiological function and partial oxygen pressure of patients with ILD are influenced by BAL process.