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Castleman disease in pregnancy.

Y Abramov¹, M Nadjari, A Abrahamov

¹Department of Obstetrics and Gynecology, and Pathology, Hadassah Hebrew University Medical Center, Ein-Kerem, Israel.

Obstetrics and Gynecology

|January 5, 2002

Summary

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Castleman disease, a rare lymphoid disorder, can present as an abdominal mass during pregnancy. This case highlights the importance of considering this benign condition in pregnant patients with abdominal masses.

Area of Science:

Reproductive Medicine
Oncology
Pathology

Background:

Castleman disease is a rare lymphoproliferative disorder.
Typically presents as a solitary mediastinal mass.
Pregnancy is an unusual context for Castleman disease presentation.

Observation:

A pregnant patient in her second trimester presented with a large abdominal mass and vaginal bleeding.
Imaging revealed a large, vascularized retroperitoneal solid mass.
Surgical exploration identified a mesenteric mass consistent with hyaline-vascular Castleman disease.

Findings:

Histological analysis confirmed hyaline-vascular Castleman disease.
Complete surgical excision of the mass was achieved.
The patient experienced an uneventful postoperative recovery but later had preterm labor.

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Implications:

Castleman disease should be included in the differential diagnosis for abdominal masses during pregnancy.
Early recognition and management are crucial for maternal and fetal well-being.
This case expands the known clinical presentations of Castleman disease.