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Related Concept Videos

Overview of Fungi01:29

Overview of Fungi

Fungi are a diverse group of eukaryotes more closely related to animals than other eukaryotes. Fungal cell walls comprise chitin, a polysaccharide that provides structural strength, and glucans, which contribute to flexibility and integrity. Other polysaccharides, such as mannans and galactosans, may supplement or replace chitin in some fungi. These adaptations, along with their preference for acidic environments and tolerance for high osmotic pressure, enable fungi to thrive in various...
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...
Microbe-Plant Interactions01:09

Microbe-Plant Interactions

Microbe-plant interactions represent a dynamic spectrum of associations shaped by intricate chemical signaling. These interactions can be neutral, beneficial, or detrimental, and profoundly influence plant physiology, growth, and ecosystem function. The plant microbiome, comprising bacteria, fungi, archaea, protists, and viruses, plays a pivotal role in mediating these effects through surface colonization, internal colonization, or systemic symbiosis.Mutualistic associations, particularly with...
Biodeterioration01:28

Biodeterioration

Biodeterioration refers to the unwanted alteration of materials caused by microorganisms—especially fungi—which damage both organic substrates (paper, wood, textiles) and inorganic ones (stone, plaster, glass). Unlike abiotic decay, biodeterioration results from biological activity that produces physical disruption and chemical degradation.Physical deterioration occurs as fungal hyphae penetrate pores, cracks, and surface irregularities. Hyphal turgor pressure, thigmotropic growth along...

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Updated: Jul 17, 2026

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

Fungi: toxic killers or unavoidable nuisances?

H A Burge1

  • 1Harvard School of Public Health, Boston, Massachusetts 02215, USA. hburge@hsph.harvard.edu

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|January 5, 2002
PubMed
Summary

Fungal exposure primarily causes allergic disease. The evidence linking inhaled mycotoxins to human illness in homes and offices is very weak, despite extensive research.

Area of Science:

  • Mycology
  • Environmental Health
  • Toxicology

Background:

  • Fungi are ubiquitous in indoor environments and have diverse roles in human health.
  • Mycotoxins, toxic secondary metabolites produced by fungi, are a concern for indoor air quality.
  • The relationship between fungal exposure, mycotoxins, and human health requires careful evaluation.

Purpose of the Study:

  • To review the literature on the roles of fungi in human health.
  • To critically assess the evidence for mycotoxin-induced diseases from inhalation exposure.
  • To provide perspective on the current understanding of fungal and mycotoxin health effects.

Main Methods:

  • Comprehensive literature search of PubMed and other recognized sources.
  • Inclusion of peer-reviewed studies and established texts.

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Microfluidic Tools for Probing Fungal-Microbial Interactions at the Cellular Level

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  • Focus on studies investigating fungal exposure and mycotoxin effects on human health.
  • Main Results:

    • Numerous studies link fungal exposure to allergic diseases.
    • No systematic documentation was found for mycotoxin-induced allergic or other diseases via inhalation.
    • Case studies lacked unequivocal evidence of a cause-and-effect relationship between inhaled mycotoxins and human illness in common settings.

    Conclusions:

    • Allergic disease is the predominant health outcome associated with fungal exposure.
    • The scientific evidence for inhalation-induced diseases from mycotoxin exposure in residential and office environments is notably weak.
    • Further research may be needed to clarify specific exposure-disease relationships, but current evidence is limited.