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Related Experiment Videos

Unusual urticarias.

A K Black1

  • 1St John's Institute of Dermatology, Kings College, St. Thomas' Hospital, London, UK.

The Journal of Dermatology
|January 5, 2002
PubMed
Summary
This summary is machine-generated.

Atypical urticarias persist longer than 24 hours and may present with systemic symptoms, unlike typical hives. Conditions like urticarial vasculitis require different treatments beyond antihistamines.

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Area of Science:

  • Dermatology
  • Immunology
  • Genetics

Background:

  • Urticarial lesions are transient, itchy swellings typically resolving within 24 hours.
  • Angioedema involves similar subcutaneous lesions.
  • Atypical urticarias are distinguished by prolonged duration (>24 hours), potential pain, bruising, and systemic symptoms.

Purpose of the Study:

  • To differentiate between typical and atypical urticarial presentations.
  • To highlight conditions with prolonged weals, such as delayed pressure urticaria and urticarial vasculitis.
  • To discuss rare urticarial syndromes and their genetic associations.

Main Methods:

  • Clinical description of urticarial lesion characteristics.
  • Histological features of urticarial vasculitis (venulitis).

Related Experiment Videos

  • Review of associated systemic symptoms and genetic links.

    • Main Results:

    • Delayed pressure urticaria and urticarial vasculitis are prolonged urticarial conditions unresponsive to antihistamines.
    • Urticarial vasculitis shows venulitis histologically and may involve arthralgia and abdominal pain.
    • Rare syndromes like Schnitzler's, Still's, Muckle-Wells, and cold urticaria have distinct features and genetic links.

    Conclusions:

    • Prolonged urticarial lesions necessitate evaluation beyond typical urticaria, considering conditions like urticarial vasculitis.
    • Specific urticarial syndromes and physical urticarias have unique clinical and genetic profiles.
    • Accurate diagnosis is crucial as atypical presentations may mimic other dermatological conditions or drug reactions.