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[Energetics of hydratation of nucleic acids with various nucleotide composition]
A I Gasan1, K M Virnik, V Ia Maleev
1Institute of Radiophysics and Electronics, National Academy of Sciences of Ukraine, ul. Akademika Proskury 12, Kharkov, 310085 Ukraine.
Biofizika
|January 5, 2002
Abstract:
The hydration energetics of natural DNA with various AT/GC-composition and model double-helix polyribonucleotides was studied using a new approach which is based on calorimetric measurements of the dehydration energy of nucleic acid-water systems at various levels of relative humidity. A linear correlation between the dehydration energy and the nucleotide composition of natural DNA was found.