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r-hirudin as anticoagulant for cardiopulmonary bypass
1Department of Anaesthesia, Waikato Hospital, Hamilton, New Zealand.
Anaesthesia and Intensive Care
|January 5, 2002
Abstract:
A 68-year-old woman with unstable angina and an episode of ventricular fibrillation developed a persistent and recurrent rash due to heparin. Medical therapy was continued with danaproid. For cardiopulmonary bypass and coronary artery grafting, r-hirudin was used as the anticoagulant. There were no thrombotic or coagulopathic complications. There is still no ideal alternative to unfractionated heparin for anticoagulation for cardiopulmonary bypass. The use of r-hirudin was successful and we describe our anticoagulant strategy.