Related Experiment Video

Updated: Aug 19, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

Use of propofol sedation in a pediatric emergency department: a prospective study

E G Skokan1, C Pribble, K E Bassett

  • 1Department of Pediatrics, Primary Children's Medical Center, University of Utah School of Medicine, Salt Lake City 84113, USA.

Clinical Pediatrics
|January 5, 2002
PubMed

Insights

Propofol is an effective and safe sedation for pediatric emergency procedures. This study found it led to excellent satisfaction with minimal complications, making it suitable for children needing painful interventions.

Area of Science:

  • Pediatric Emergency Medicine
  • Anesthesiology
  • Pharmacology

Background:

  • Procedural sedation in emergency departments is crucial for pediatric care.
  • Propofol offers rapid onset and offset, making it a potential option for children.

Purpose of the Study:

  • To evaluate the efficacy and safety of propofol for procedural sedation in pediatric emergency patients.
  • To assess patient and operator satisfaction and recovery times.

Main Methods:

  • Intravenous propofol administration for painful procedures in children.
  • Monitoring of vital signs, complications, and recovery.
  • Assessment of amnesia and satisfaction levels.

Main Results:

  • Mean age 7.4 years; 65% male; most underwent fracture reduction.
  • Mean propofol dose 3.3 mg/kg; 30% experienced desaturation; one required ventilation.
  • Most patients had decreased blood pressure; mean recovery time 18 minutes.

Conclusions:

  • Propofol is effective for sedation in pediatric emergency settings.
  • It demonstrates a favorable safety profile with generally minimal complications.
  • High satisfaction rates among patients, parents, and operators were observed.

More Related Videos

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device09:36

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Published on: September 24, 2020

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

Related Concept Videos

Stages of General Anesthesia01:22

Stages of General Anesthesia

Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
Inhalational Anesthetics: Overview01:20

Inhalational Anesthetics: Overview

Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...