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Choosing therapy for childhood asthma.

¹University of Wisconsin Children's Hospital, H4/432, 600 Highland Avenue, Madison, WI 53792, USA. rfl@medicine.wisc.edu

Paediatric Drugs

|January 5, 2002

Summary

Inhaled corticosteroids are the main treatment for childhood asthma. Other options like leukotriene receptor antagonists and omalizumab offer alternatives for better asthma control.

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Area of Science:

Pediatric Pulmonology
Allergy and Immunology
Pharmacology

Background:

Childhood asthma management relies primarily on inhaled corticosteroids.
Alternative and adjunctive therapies are crucial for optimizing asthma control.

Purpose of the Study:

To review current pharmacological approaches for childhood asthma.
To discuss the efficacy and role of various asthma medications.

Main Methods:

Literature review of asthma treatment guidelines and clinical trials.
Analysis of different drug classes including corticosteroids, bronchodilators, and novel therapies.

Main Results:

Inhaled corticosteroids are first-line therapy.
Long-acting beta(2)-agonists, theophylline, leukotriene receptor antagonists, and omalizumab serve as adjuncts or alternatives.
Inhalation device choice is individualized based on patient factors.

Conclusions:

A stepwise approach utilizing various medications is essential for effective childhood asthma management.
Novel therapies like omalizumab show promise in addressing underlying asthma pathology.

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