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Risk factors for new atherothrombotic brain infarction in older Hispanic men and women

Wilbert S Aronow1, Chul Ahn

  • 1Hebrew Hospital Home, Bronx, New York, USA. WSAronow@aol.com

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
|January 5, 2002
PubMed

Insights

Atherothrombotic brain infarction (ABI) is common in older Hispanic adults in long-term care. Key risk factors for new ABI include age, smoking, diabetes, prior ABI, and cholesterol levels.

Area of Science:

  • Gerontology
  • Neurology
  • Epidemiology

Background:

  • Investigates the prevalence and incidence of atherothrombotic brain infarction (ABI) in an elderly Hispanic population residing in a long-term care facility.
  • Focuses on a specific demographic group to understand stroke risk factors in a unique healthcare setting.

Purpose of the Study:

  • To determine the prevalence and incidence of ABI in older Hispanic men and women.
  • To identify significant independent risk factors associated with new ABI in this population.

Main Methods:

  • A cohort of 201 Hispanic men (mean age 79) and 302 Hispanic women (mean age 80) in a long-term care facility were followed.
  • Mean follow-up periods were 42 months for men and 47 months for women.
  • Prevalence, incidence, and associations between risk factors and new ABI were analyzed.

Main Results:

  • The prevalence of prior ABI was 33% in men and 30% in women.
  • The incidence of new ABI was 24% in men and 23% in women over the follow-up period.
  • Identified significant risk factors including age, smoking, hypertension, diabetes, prior ABI, total cholesterol, and HDL cholesterol.

Conclusions:

  • Age, current cigarette smoking, diabetes mellitus, prior ABI, serum total cholesterol, and serum HDL cholesterol are significant independent risk factors for new ABI in older Hispanic men and women.
  • Hypertension was also a significant independent risk factor specifically in older Hispanic men.
  • These findings highlight modifiable and non-modifiable factors contributing to stroke risk in this vulnerable population.
Abstract

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