Growth dependent changes of glycolipid compositions of mouse ascites tumor cells

Total glycolipid compositions of mouse ascites tumor cells harvested at various growth stages with different growth rate were compared. MM2, MH134, Ehrlich and L1210 cells were used. Some growth dependent changes common among different cells strains were observed: (1) the amount of ganglyosides generally increased with decreasing growth rate of the cells; (2) an unidentified minor ganglyoside (X2) having a strong reverse corelation with the growth rate of the cells was found; and (3) the amount of CMH, GM3 and another unidentified ganglyoside (X1) had positive corelation with the growth rate.