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Use of rabies vaccines after reconstitution and storage
Pakamatz Khawplod1, Tanpetch Tantawichien, Henry Wilde
1Queen Saovabha Memorial Institutes, Thai Red Cross Society and Department of Medicine, King Chulalongkorn University Hospital, Bangkok, Thailand.
Abstract:
Storing freshly reconstituted purified chick embryo rabies vaccine at 4 degrees C for 1 week allowed use of <1 ampoule of 1.0 mL for 1 patient for day 0, 3, and 7 immunizations, representing considerable savings in vaccine and also possibly allowing use of this cost-saving regimen in centers that see <1 rabies-exposed patient daily. The 90-day booster dose mandated in the current intradermal regimen may not be necessary if the day 28 dose is doubled, eliminating 1 clinic visit at no additional cost in vaccine.