Related Experiment Video
Updated: Oct 3, 2026

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
[An experimental study on the regenerating ability of the condylar cartilage of the rabbit]
Objective:
To investigate the regenerating ability of the condylar cartilage of the adult rabbit.
Methods:
A fullthickness defect was created in the condylar cartilage of the adult rabbit, with or without penetrating into the subchondral bone.
Results:
In the cases of the condylar cartilage defect without penetration into the subchondral bone, the defects were repaired with fibrous tissue partly. However, in those the defect penetrated the subchondral bone, the defects were repaired with cartilage-like tissue at four and eight weeks periods, then the regenerated tissue transformed into the bone-like tissue.
Conclusion:
The defect of the condylar cartilage can't be repaired with cartilage, and the reparative cells were the undifferentiated mesenchymal cells originated from the bone marrow.

