Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Inhalation sedation with nitrous oxide in dental extraction].

Y Sun1, D Qi, B Zhang

  • 1Department of Stomatology, Beijing Tongren Hospital, Beijing 100730.

Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology
|January 5, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Technique of implanting 17 alpha-methyltestosterone to induce the sex reversal of Epinephelus malabaricus].

Ying yong sheng tai xue bao = The journal of applied ecology·2002
Same author

[Effect of different source iron on piglet's growth, metabolism and environment].

Ying yong sheng tai xue bao = The journal of applied ecology·2002
Same author

[Factors affecting colonization of introduced microorganisms on plant roots].

Ying yong sheng tai xue bao = The journal of applied ecology·2002
Same author

[Gastric evacuation rate of black sea bream(Sparus macrocephalus)].

Ying yong sheng tai xue bao = The journal of applied ecology·2002
Same author

[Assimilation efficiency of pacific oyster Crassortrea gigas].

Ying yong sheng tai xue bao = The journal of applied ecology·2002
Same author

[Correction of nasal deformity in unilateral cleft lip of adult cases].

Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery·2002
Same journal

[Clinical significance and molecular mechanisms of m<sup>6</sup>A modification in oral squamous cell carcinoma].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology·2026
Same journal

[Oral-gut axis: the microbial and immune bridge linking periodontitis to inflammatory bowel disease].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology·2026
Same journal

[Progress in basic research on hydrogel-based drug delivery systems for the treatment of peri-implantitis].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology·2026
Same journal

[Application of splint to relieve muscle symptom caused by clenching in a mandible osteomyelitis patient: a case report].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology·2026
Same journal

[Digital technology assisted rehabilitation with an adhesive retained auricular prosthesis: a case report].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology·2026
Same journal

[Exploring innovative approaches by Zhu Xitao to promote the modernization and internationalization of Chinese stomatology].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology·2026
See all related articles

Nitrous oxide inhalation sedation significantly reduces pain and anxiety during dental extractions compared to local anesthesia alone. Most patients preferred this method for its calming and memory-impairing effects.

Area of Science:

  • Dentistry
  • Anesthesiology
  • Pharmacology

Background:

  • Dental extractions can cause significant patient anxiety and discomfort.
  • Conscious sedation techniques are employed to improve patient experience during dental procedures.

Purpose of the Study:

  • To evaluate the benefits of nitrous oxide (N2O) inhalation sedation during dental extractions.
  • To compare N2O sedation with local anesthesia alone and assess the impact of estazolam.

Main Methods:

  • 112 patients were randomized into four groups receiving varying concentrations of N2O, with or without estazolam.
  • N2O was administered as conscious sedation adjunct to local anesthesia.
  • A control group (53 patients) received only local anesthesia.

Related Experiment Videos

Main Results:

  • The N2O group showed significantly lower postoperative pain scores (MDAS) compared to the control group (P < 0.01).
  • Patients receiving N2O experienced sedation and partial amnesia.
  • 86.62% of patients preferred N2O inhalation sedation.
  • No significant differences in anxiolytic, sedative, or amnestic effects were found among the N2O groups; estazolam showed no additional benefit.

Conclusions:

  • Inhalation sedation with nitrous oxide is effective for dental extractions, providing anxiolysis, sedation, and amnesia.
  • N2O offers a preferred method for managing patient comfort during dental procedures.