Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Development of the human gracilis nucleus: a morphometric evaluation.

X Ma1, N Goto, J Goto

  • 1Department of Anatomy, Showa University School of Medicine, 5-8, Hatanodai 1, Shinagawa-Ku, Tokyo 142-8555, Japan.

Okajimas Folia Anatomica Japonica
|January 5, 2002
PubMed
Summary

The human gracilis nucleus develops gradually from 18 weeks gestation, showing normal apoptosis and an unexplained neuron-neuropil discrepancy. This study tracks its growth in fetuses, infants, and adults.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative Analysis Between Strip and Gels Indicated for at Home Bleaching: Analysis of Color Alteration, Roughness and Microhardness of Dental Enamel.

Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]·2025
Same author

Evaluation of health and quality of life in apheresis patients - data from the WAA register.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2019
Same author

Morphological analysis of tendinous structure in the American alligator jaw muscles.

Journal of morphology·2018
Same author

Subnanosecond In-Line Soft X-Ray Holography Using Germanium Laser in the 20 nm Wavelength Region.

Journal of X-ray science and technology·2011
Same author

IFNβ-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum.

Neurology·2010
Same author

TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.

Oncogene·2009

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Human Anatomy

Background:

  • The gracilis nucleus is a key component of the human brainstem.
  • Understanding its development is crucial for identifying potential neurological abnormalities.

Purpose of the Study:

  • To investigate the developmental trajectory of the human gracilis nucleus.
  • To characterize morphometric changes and identify developmental phenomena.

Main Methods:

  • Morphometric analysis of serial brain sections from fetuses (18-40 weeks gestation), an infant, and an adult.
  • Utilized microscopy with a drawing tube and an image-analyzing computer system.

Main Results:

  • Neurons were distinguishable from glia starting at 18 weeks gestation.

Related Experiment Videos

  • Observed gradual development in columnar volume, neuronal size, and neuronal number.
  • Identified natural cell death (apoptosis) and an unexplained discrepancy between neuron count and neuropil index.

    • Conclusions:

    • The human gracilis nucleus undergoes significant development during gestation and early infancy.
    • Apoptosis is a normal developmental process within this nucleus.
    • An unexplained neuron-neuropil index discrepancy warrants further investigation.