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The STR locus D11S554: allele frequencies and sequence data in a Japanese population
Y Watanabe1, A Nagai, T Takayama
1Department of Legal Medicine, Gifu University School of Medicine, Japan. watayosh@sannet.ne.jp
International Journal of Legal Medicine
|January 5, 2002
Summary
This study analyzed the short tandem repeat (STR) locus D11S554 in Japanese individuals. The D11S554 locus proved to be a valuable genetic marker for forensic applications in this population.
Area of Science:
- Genetics
- Forensic Science
- Population Studies
Background:
- Short tandem repeat (STR) loci are crucial for human identification.
- Understanding population-specific genetic variation is essential for forensic applications.
Purpose of the Study:
- To characterize the genetic variability of the STR locus D11S554 in a Japanese population.
- To evaluate the utility of D11S554 as a genetic marker for forensic purposes.
Main Methods:
- Population study involving 362 unrelated Japanese individuals from Gifu Prefecture.
- Analysis of 46 alleles and 135 genotypes at the D11S554 locus.
- Sequence analysis of 185 alleles to determine repeat region structures and identify new sequence types.
Main Results:
- Identified 46 distinct alleles and 135 genotypes at the D11S554 locus.
- Discovered nine sequence types, including four novel ones (IA3, IA4, IA5, IB3).
- Observed sequence heterogeneity in 11 out of 46 alleles, indicating complex repeat structures.
Conclusions:
- The D11S554 locus exhibits significant genetic diversity in the Japanese population.
- D11S554 is a powerful and useful genetic marker for forensic identification in Japanese individuals.
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