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Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
Published on: August 5, 2014
Brain MRI of hippocampal volumetry in patients with refractory temporal lobe epilepsy
1Department of Medicine, Queen Elizabeth Hospital, Kowloon, Hong Kong SAR, China.
Objective:
To detect for hippocampal sclerosis presurgically in a group of patients with refractory temporal lobe epilepsy.
Methods:
Eighty-four consecutive patients with refractory temporal lobe epilepsy were subjected to brain MRI of hippocampal volumetry. A ratio of smaller to larger hippocampal volume was determined and unilateral hippocampal atrophy (HA) was diagnosed if the ratio is less than 0.91.
Results:
Unilateral HA was diagnosed in 42 patients (50%) and bilateral HA in 1 patient. Other MRI abnormalities were detected in 18 patients with or without coexisting HA.
Conclusions:
Hippocampal sclerosis can be detected presurgically in many patients by brain MRI. Additional abnormalities not detected by brain CT can also be demonstrated.
