Related Experiment Video
Updated: Oct 3, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
Published on: July 14, 2023
Non-surgical therapy of primary hyperparathyroidism
P Howell1, S Kariampuzha, W Kipgen
1Oklahoma Medical Research Foundation, 825 NE 13th Street, Mail Stop 24, Oklahoma City, OK 73104, USA.
Background:
Primary hyperparathyroidism is a commonly encountered illness that can usually be treated successfully with surgery. However, non-surgical ablation by either infusion of contrast media via angiography or percutaneous injection of ethanol has been reported from a few medical centers.
Methods:
All patients undergoing non-surgical treatment of primary hyperthyroidism at the University of Oklahoma Health Sciences Center were identified and their records reviewed.
Results:
We have used non-surgical techniques to treat three patients with primary hyperparathyroidism. The patients were considered poor surgical candidates or had persistent hypercalcemia after neck exploration. Hypercalcemia was improved or cured in each of the patients without recurrence.
Conclusions:
Our application of these techniques indicates that centers without extensive experience can successfully employ angiographic or ethanol ablation of parathyroid adenomas.
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