[Characteristics of the virus and of measles vaccines (author's transl)]
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Abstract:
Characteristics of measles virus and some aspects of virus-cell interaction are reported. For their interest, findings from recents investigations on comparison between SSPE isolates and wild strains are summarized. Both inactivated and live attenuated measles vaccines are then briefly described. The former has been used in the U.S.A. from 1963 to 1968 and discontinued thereafter mainly for safety problems, the latter, prepared with Schwarz or with Moraten strain, are in use today for the prophylaxis against measles.
Insights
This study details measles virus characteristics and interactions, comparing SSPE and wild strains. It reviews inactivated and live attenuated measles vaccines, noting the former
Area of Science:
- Virology
- Immunology
Context:
- Measles virus characteristics and pathogenesis.
- Virus-cell interaction mechanisms.
Purpose:
- Summarize recent findings comparing SSPE isolates and wild measles virus strains.
- Describe inactivated and live attenuated measles vaccines.
Summary:
- Discusses measles virus properties and interactions.
- Compares subacute sclerosing panencephalitis (SSPE) isolates with wild measles strains.
- Reviews historical inactivated and current live attenuated measles vaccines.
Impact:
- Provides insights into measles virus biology and vaccine development.
- Informs understanding of vaccine safety and efficacy for measles prevention.