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[Study on ascite of ovarian cancer]
1Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.
Objective:
Analysis of correlative factors in ascite of ovarian cancer.
Methods:
The clinical data of 72 patients with ovarian cancer admitted to our hospital from 1993 to 1998 were analyzed retrospectively.
Results:
73.5% of patients with ovarian cancer had cancer cells in ascite, the incidence of ascite was 81.9%, III and IV stage ovarian cancer with cancer cells in ascite were 91.2%, positive rate of tumor cells obviously increased in cases whose ascite were more than 1,000 ml, in cases with tumor surface infiltration as well as with metastasis to omentum, intestine and diaphragm. CA125 value in ascite without cancer cells was (324.94 +/- 527.64) kU/L, whereas in ascite with cancer cells it was (5,172.64 +/- 1,432.61) kU/L. Whether cancer cells were positive or negative. Chromosomal aneuploidy was detected in two third of the cases.
Conclusion:
Routine examination of cancer cells, chromosome and CA125 in ascite with ovarian cancer may improve the diagnostic accuracy.