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[Expression of leukemia inhibitory factor in human decidua]
1Department of Obstetrics and Gynecology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Zhonghua Fu Chan Ke Za Zhi
|January 5, 2002
Abstract
Objective:
To study the expression and localization of leukemia inhibitory factor (LIF) in human first trimester decidual.
Method:
By immunohistochemical analysis and in situ hybridization, the LIF mRNA and protein expression were observed in 16 cases of human decidua.
Results:
LIF mRNA and protein expressions were observed in all decidual specimens, the glanduar epithelium showed higher LIF expression than in stromal cells.
Conclusion:
Expression of LIF in human decidua may contribute to embryo implantation, maintenance of placental functions and embryonic growth promation.