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[Radiotherapy for early anal cancer: a report of 27 cases]
1Cancer Istitute (Hospital), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021.
Objective:
To evaluate the results of radiotherapy for early stage anal cancer.
Methods:
During 1960 through 1993, 27 patients with stage T1-2N0 anal cancer were treated by radiotherapy alone. Seven cases received pelvic irradiation plus local field boost, 20 cases received local field irradiation alone. Kaplan-Meier method was used in survival analysis.
Results:
The overall 5-year survival rate in this series of patients was 79.1%. Eighteen of the 27 cases had their anal functions preserved. Local recurrence occurred in 7 cases and regional lymph node metastasis in one case. Five of them were salvaged, two by surgery and three by irradiation.
Conclusion:
Radiotherapy alone for early anal cancer is effective. Anal function is preserved in about two-thirds of the patients so treated. Local treatment failure can be salvaged by surgery or radiotherapy.
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