[A clinical retrospective review of stage IB1 and IB2 cervical cancer]

To investigate the prognostic factors and treatment of cervical cancer in stage IB1 and IB2.

Three hundred fifty-six patients with stage IB cervical cancer were treated with redical hysterectomy. Seventy two patients received preoperative radiation (IB1 n = 39, IB2 n = 33), 83 patients received postoperative radiation (IB1 n = 61, IB2 n = 22), 11 patients received radiation before and after operation (IB1 n = 5, IB2 n = 6).

Two hundred forty nine patients had been followed up for more than 5 years. The overall 5-year survival rate was significantly higher in patients in stage IB1 than in stage IB2. In patients with deep tumor invasion of the cervical matrix, the difference in 5-year survival was also significantly different between patients in stage IB1 and IB2. However, no significant difference was observed between the 2 groups of patients with positive nodes, nor was it related to tumor cell differentiation. Patients treated with surgery alone had similar 5-year survival rates but it was significantly higher in stage IB1 than in stage IB2 patients who received preoperative radiotherapy. Post-operative radiotherapy did not help survival in both groups of patients.

The survival rate of cervical cancer in stage IB1 significantly differs from that in stage IB2. However, postoperative radiotherapy does not help improve survival of stage IB1 and IB2 patients with high risk factors.