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[Histomorphometry of silicon nitride composite endosteal implant in dogs]
Objective:
To study the dynamic changes of bone interface with silicon nitride (Si3N4) composite implants.
Methods:
4 Beagle dogs were experimental animals, Si3N4-HA and pure Si3N4 implant were experimental group, and Ti and Ti-HA were used as comparisons. They were implanted into dogs' femurs by stages. Histomorphometry was used to analyse and compare bone growth metabolism of bone interface with implant as well as evaluation of biocompatibility from quantitative and dynamic aspects.
Results:
Parameters expressing mineralization and speed of deposition at the Si3N4-HA bone interface were higher than comparisions' at the first month. After 6 months, pure Si3N4's bone histomorphometic parameters had no notable difference with others.
Conclusion:
New implant material is useful to the clinic. The histomorphometry is of much value for the study of interface bone metabolism from quantitative and dynamic point of view.