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[Regulation of adherence to serum-coated hydroxyapatite by Streptococcus sanguis]
Objective:
To investigate the effects of pH and calcium iron on adhesion of Streptococcus sanguis to serum-coated hydroxyapatite.
Methods:
The adhesion model in vitro established by Clark W. B. in 1977 was used to quantify adsorptive cells through [3H] thymidine labelling.
Results:
The cpm values between different pH groups showed significant differences. Also, there were significant differences of cpm values between calcium groups and control group.
Conclusion:
Either pH or calcium iron has obvious effect on adherence of Stroptococcus sanguis to serum-coated hydroxyapatite. The findings suggest that regulating pH and concentration of calcium iron can help to change colonization on teeth surfaces by Streptococcus sanguis in periodontal circumstance.