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[Research progress of fibroblast and wound repair]
1Department of Pediatric Surgery, First University Hospital, West China University of Medical Sciences, Chengdu Sichuan, P. R. China 610041.
Abstract
Objective:
To review the recent advances in fibroblast study and its role in wound repair.
Methods:
Recent original articles related to wound repair were retrieved extensively, and the effect of fibroblast on every stages of repair were summed up and comprehended.
Results:
Fibroblast plays important roles in granulation formation, wound contraction, matrix synthesis, wound repair, scar formation and scarless repair by means of growth factors modulation.
Conclusion:
The understanding of fibroblast in the wound repair can promote the progress of biological therapy of wound repair and scar prevention.