Related Experiment Video
Updated: Aug 7, 2026

Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat
Published on: February 5, 2011
Carotid dissection: a common cause of Horner's syndrome
1Department of Neuro-Ophthalmology, The Royal Victorian Eye and Ear Hospital, East Melbourne, Australia. chunkeng@yahoo.com
Insights
Internal carotid artery dissection frequently causes Horner's syndrome. Prompt diagnosis and anticoagulation treatment are crucial to prevent serious complications like carotid thrombosis and embolism.
Area of Science:
- Neurology
- Vascular Surgery
- Ophthalmology
Background:
- Internal carotid artery dissection (ICAD) is a significant cause of secondary Horner's syndrome.
- Prompt diagnosis is essential for effective management and prevention of cerebrovascular events.
Observation:
- Five case reports illustrate Horner's syndrome resulting from ICAD, with varied etiologies including trauma and spontaneous dissection.
- Literature review confirms ICAD is an under-recognized cause of Horner's syndrome, often missed in clinical practice.
Findings:
- Magnetic resonance imaging and angiography (MRA) of the head and neck are the preferred diagnostic modalities for ICAD.
- Anticoagulation therapy for 3-6 months is the recommended treatment for carotid dissection.
Implications:
- Clinicians should maintain a high index of suspicion for ICAD in patients presenting with Horner's syndrome, especially with concurrent head or neck pain.
- Timely diagnosis and anticoagulation can prevent debilitating outcomes such as stroke and systemic embolism.
Purpose:
To highlight that internal carotid artery dissection is a common cause of Horner's syndrome and that it is important to diagnose dissection as anticoagulation can prevent carotid thrombosis and embolism.
Methods:
Five case reports are presented of patients with Horner's syndrome secondary to carotid dissection. One patient had carotid dissection secondary to trauma, two had spontaneous dissections and two had dissections in the settings of other illness. A literature search was performed on carotid dissection as a cause of Horner's syndrome and its diagnosis and management.
Results:
The case reports and literature highlight that dissection is under-recognized as a cause of Horner's syndrome and can be missed. The investigation of choice is a magnetic resonance imaging and angiography scan of the head and neck. The treatment advocated is anticoagulation for 3-6 months.
Conclusion:
Carotid dissection should be suspected in patients with Horner's syndrome, particularly if head or neck pain is present.
Related Concept Videos
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's phenomenon, is a...
The Arch of Aorta
Encircling the heart, the coronary arteries form a ring-like structure before...
Arteries of the Head and Neck
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Hemorrhagic Stroke l: Introduction
Transient Ischemic Attack l: Introduction

