Related Experiment Video

Updated: Aug 7, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

[Continuous negative pressure (cnp) in infants with idiopathic respiratory distress syndrome (irds) (author's

H Wolf, T Suermann, A Schacht

    Monatsschrift Fur Kinderheilkunde
    |October 1, 1975
    PubMed

    Insights

    Continuous negative pressure (CNP) therapy in a chamber improved outcomes for premature infants with idiopathic respiratory distress syndrome (IRDS). This method is beneficial for early to medium-severe IRDS cases.

    Area of Science:

    • Neonatology
    • Pediatric Respiratory Medicine

    Context:

    • Idiopathic respiratory distress syndrome (IRDS) is a common condition in premature infants.
    • Previous treatment outcomes for IRDS showed significant mortality rates.

    Purpose:

    • To evaluate the efficacy of continuous negative pressure (CNP) therapy in a chamber for treating infants with IRDS.
    • To compare mortality rates and clinical responses in infants treated with CNP versus standard care.

    Summary:

    • 13 premature infants with IRDS were treated with CNP therapy. Mortality in the CNP group was 4/13, compared to 6/13 in a differently treated group and 18/27 in the previous year.
    • Infants receiving CNP showed decreased respiratory frequency, reduced grunting, and improved skin color.
    • Pathological findings in deceased infants included atelectasis and interstitial emphysema; one infant died from coagulopathy. One survivor developed hydrocephalus.

    Impact:

    • CNP therapy in a chamber is a valuable treatment for early to medium-severe IRDS.
    • Early application of CNP may prevent the development of severe IRDS.
    • CNP therapy is not recommended for severe cases of IRDS.

    More Related Videos

    How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children07:27

    How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children

    Published on: August 19, 2020

    Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs05:40

    Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs

    Published on: December 22, 2023

    Related Concept Videos

    Pressure Relationships in Thoracic Cavity01:24

    Pressure Relationships in Thoracic Cavity

    Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
    Breathing Mechanisms
    Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs during...
    Pulmonary Cycle: Exhalation01:17

    Pulmonary Cycle: Exhalation

    In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
    Suctioning the Nasopharyngeal Airway01:29

    Suctioning the Nasopharyngeal Airway

    Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
    Equipment Required
    Mechanical Ventilation II: Invasive Ventilation01:23

    Mechanical Ventilation II: Invasive Ventilation

    Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
    Negative-Pressure Ventilators
    Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
    Mechanical Ventilation III: Noninvasive Ventilation01:23

    Mechanical Ventilation III: Noninvasive Ventilation

    Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
    Noninvasive Positive-Pressure Ventilation (NIPPV)
    Respiratory Syncytial Virus Disease01:29

    Respiratory Syncytial Virus Disease

    Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...