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Cytogenetic analysis in 61 couples with spontaneous abortions
1Department of Pediatrics, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China.
Chinese Medical Journal
|January 10, 2002
Abstract
Objective:
To examine the relationship between spontaneous abortion and chromosomal abnormalities.
Methods:
Couples who had one or more consecutive spontaneous abortions and had normal genitals were enrolled for cytogenetic karyotype analysis.
Results:
In the 61 couples, the detected incidence was 11.5%, with five Robertsonian translocations, one reciprocal translocation, and one pericentric inversion of chromosome 7.
Conclusion:
Chromosomal abnormalities may play an important role in fetal wastage.