Related Experiment Video
Updated: Oct 3, 2026
Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
Published on: August 5, 2014
Determination of the dominant language hemisphere by functional MRI in patients with temporal lobe epilepsy
1Department of Neurosurgery, Huashan Hospital Shanghai Medical University, Shanghai 200040, China.
Objective:
To determine the dominant language hemisphere in patients with intractable temporal lobe epilepsy before surgical treatment by using functional MRI (fMRI).
Methods:
Twelve patients underwent fMRI. Among them, 4 patients also underwent the Wada test. Anterior temporal lobectomy was performed on patients with epileptic focus on the non-dominant hemisphere, and selective amygdalo-hippocampectomy on patients with epileptic focus on the dominant hemisphere.
Results:
Ten patients had left dominance, and 2 right dominance. The fMRI results were concordant with Wada test results in the 4 patients who accepted the Wada test. Seven patients underwent anterior temporal lobectomy, and 5 underwent selective amygdalo-hippocampectomy. There was no post-operative dysphasia.
Conclusion:
fMRI is an alternative method of noninvasive functional mapping for language dominance in patients with temporal lobe epilepsy.
More Related Videos
Related Concept Videos
01:28Lateralization
01:10Higher Mental Functions of the Brain: Language
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
01:05Cerebral Hemispheres